Brain Injury and Concussion Research

This study aimed to: (1) identify predictors of post-SRC neck pain, (2) assess its impact on symptom severity, and (3) determine its association with prolonged recovery.

​Objective: To compare clinical characteristics, treatment patterns, and patient-reported outcome measures (PROMs) in persons with persistent post-traumatic headache (PTH) and those with episodic or chronic migraine (with and without medication-overuse headache).

Objective: Traumatic brain injury (TBI) remains a leading cause of mortality and disability globally, necessitating ongoing research into its pathophysiology and management. This review compiles current knowledge on TBI, focusing on its mechanisms, updated clinical guidelines, and recent clinical trials.

2025 marked a turning point in traumatic brain injury (TBI) research, with studies now showing that TBI is a chronic condition characterised by prolonged biomarker elevations and long-term comorbidities, fundamentally shifting clinical management from acute intervention to lifelong monitoring and care. A new TBI classification framework was developed that captures the heterogeneity of TBI, which will allow for personalised treatment and targeted clinical trials. In parallel, emerging therapeutic approaches offer renewed hope for better outcomes.

​Concussion is common in sports and often shows sex‐based differences in symptom severity and recovery, with female athletes experiencing more severe, prolonged symptoms. Hormonal changes during the menstrual cycle may play a role in concussion, but research on this topic has been limited. Therefore, this scoping review aimed to investigate whether the menstrual cycle phase—both at the time of injury and after injury—influences postconcussion outcomes and symptom reporting, and whether menstrual cycle phases influence baseline assessments in the absence of injury.